General Info

Field	Value
Experiment Number	E847_21
Title	Study of the effects of high energy 8Li beam on biomolecules
Spokeperson(s)	Emil, Traykov Marie, Vanstalle Quentin, Raffy
Data Manager(s)	Emil, Traykov
GANIL Scientific Coordinator	Jean-Charles, Thomas
Collection Dates (dd-mm-yy)	Start: 13-04-2024 End: 17-04-2024
End of Embargo	17-04-2027
DOI	10.26143/ganil-2024-e847_21
DOI State	registered
Publication Year	2024
Publisher	GANIL, Large Heavy Ion National Accelerator, Caen, France
Data Curator	GANIL, Large Heavy Ion National Accelerator, Caen, France
Hosting Institution	CC-IN2P3, IN2P3’s Computing Centre, Villeurbanne, France
Size	0 GB

Abstract

E847_21 - This experiment aims assessing the interest of using 8Li beams for therapy through the evaluation of production of water radiolysis species and the damages induced on biomolecules by the 8Li beam and the emitted alpha particles. The radiolysis products of amino acids and peptides in diluted solutions was identified and quantified under irradiation. They will be compared to those formed by low-energy protons and helium ions (< 6MeV/nucleon), previously measured at IPHC (Strasbourg) and NIRS (Chiba, Japan). The depth-dose profile of 8Li was measured with polymethyl methacrylate attenuators of different thicknesses placed in front of PIPS and scintillating detectors. A direct comparison with the effects of a stable 12C beam (produced in one-neutron removal reactions) was performed during the experiment.

Technical Info

Contributors

Given Name	Family Name	Id.	Affiliation(s)
Emil	Traykov	-	IPHC, Strasbourg, France
Marie	Vanstalle		IPHC, Strasbourg, France
Quentin	Raffy		IPHC, Strasbourg, France

Institutes

Name	Id.
GANIL, CEA/DRF-CNRS/IN2P3, Caen, France
IPHC, Institut Pluridisciplinaire Hubert Curien, Strasbourg, France